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500k Medical Prize Given to American/German Researchers

Officials at the New York Hospital advised that three researchers who worked largely with cell proteins will have massive implications in the field of cancer, Alzheimer’s disease and illnesses that are degenerative. They will share one of the biggest awards in medicine and science in USA.

The Albany Medical Center will award a prize in Medicine and Biomedical Research of $500,000 to F. Ulrich Hartl who is from the Max Planck Institute of Biochemistry in Germany, Martinsried; Susan Lee Lindquist who is from the Massachusetts Institute of Technology and Arthur Horwich who is from Yale School of Medicine.

Who is F. Ulrich Hartl, Susan Lee Lindquist, and Arthur Horwich?

Susan Lee Lindquist

Susan Lee Lindquist

Susan Lee Lindquist was born June 5, 1949 and is a professor of biology at MIT. She specializes in molecular biology, focusing on the protein folding problem within a family of molecules also known as heat-shock proteins. Lindquist is well known for research that provides evidence for a new standard in genetics that are based on genetics with self-perpetuating shapes versus using DNA sequences.

F. Ulrich Hartl

F. Ulrich Hartl
Franz-Ulrich Hartl was born March 10, 1957 and is a Biochemist as well as the Managing Director of Max Planck Institute of Biochemistry. Harlt is known for working in the field of protein. Franz-Ulrich Hartl finished his M.D and Dr of medicine while attending the University of Heidelberg and then attended the Habil from the Institute of Physiological Chemistry to complete his Doctor of medicine degree. He was completed gis Postdoctoral Fellowship with at the University of Munich and then carried his Postdoctoral with the University of California.

Arthur L. Horwich

Arthur L. Horwich was born in 1951 is a Sterling Professor of Pediatrics and Genetics and biologist with the Yale school of medicine. Horwich’s research was responsible for uncovering the action of chaperonins, these are protein complexes that work together with other folding proteins.

The Process of Protein Folding

These three researchers were chosen for the fundamental discoveries that are related to the protein folding which is the last step in translating genetic details from the amino acids to the cell proteins.

Arthur L. Horwich

In modern biology, the term protein folding is considered a revolutionary concept although to the general public it may not be a familiar term. The important implications are for diseases like Alzheimer's disease, Parkinson’s disease as well as Huntington’s disease and other such neurodegenerative illnesses not forgetting drug resistance and cancer.

Previously it was thought that protein folding is when shapes of links of amino acids create exact cell structures was an unprompted process. The researchers show in separate studies that a complex system of specific proteins usually chaperone the process and guide them into place. The studies have increased hopes that manipulating the process with treatments and drugs could prevent the protein from misfolding which would cause the degenerative illnesses such as Alzheimer's, Lou Gehrig’s and Parkinson’s disease.

Where did the award come from?

The late Morris Silverman who was a businessman New York established this awarded and has been given annually since as early as 2001 to any researcher who has altered the course of medical history through research. The award will be presented formally on the 28 Sept. in Albany.